Antireflux Surgery, Barrett Esophagus, and Adenocarcinoma

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The effect of antireflux surgery on esophageal carcinogenesis in patients with barrett esophagus: a systematic review.

OBJECTIVE To determine whether patients with Barrett esophagus who undergo antireflux surgery differ from medically treated patients in incidence of esophageal adenocarcinoma and probability of disease regression/progression. SUMMARY BACKGROUND DATA Barrett esophagus is a risk factor for the development of esophageal adenocarcinoma. A question exists as to whether antireflux surgery reduces t...

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Laparoscopic antireflux surgery in the treatment of gastroesophageal reflux in patients with Barrett esophagus.

BACKGROUND Patients with gastroesophageal reflux and Barrett esophagus may represent a group of patients with poorer postoperative outcomes. It has been suggested that such patients should undergo open rather than laparoscopic antireflux surgery. HYPOTHESIS The laparoscopic approach to antireflux surgery is appropriate treatment for patients with Barrett esophagus who have symptomatic gastroe...

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Adenocarcinoma of the esophagus with and without Barrett mucosa.

HYPOTHESIS Previous studies have demonstrated an improved prognosis in patients with Barrett adenocarcinoma as compared with esophageal adenocarcinoma without Barrett. It has been suggested that an earlier presentation due to gastroesophageal reflux disease (GERD) may lead to detection of adenocarcinoma at an earlier stage. DESIGN The records of 178 patients with esophageal adenocarcinoma pre...

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Histopathology in Barrett Esophagus and Barrett Esophagus-Related Dysplasia

Pathologic specimens, both biopsies and endoscopic mucosal resections, for Barrett esophagus and Barrett-associated dysplasia and malignancy are common for pathologists in North America, and the incidence in South Asian countries seems to be increasing. Dysplasia and malignancy arising in intestinalized gastric-type mucosa raises issues in the interpretation of dysplasia and the evaluation of t...

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Familial Barrett esophagus and adenocarcinoma of the gastroesophageal junction.

Barrett esophagus was found in seven members of a single family. Two of these patients also had adenocarcinoma of the gastroesophageal junction. Among family members who did not have Barrett epithelium, one had esophageal ulcerations with dysplasia in squamous epithelium and another had an esophageal stricture. The pattern of involvement suggests autosomal dominant inheritance of Barrett esopha...

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ژورنال

عنوان ژورنال: Annals of Surgery

سال: 2007

ISSN: 0003-4932

DOI: 10.1097/sla.0b013e318070d3b7